An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: Effect modification by risk of bronchopulmonary dysplasia

LW Doyle; HL Halliday; RA Ehrenkranz; PG Davis; JC Sinclair

Journal article

An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: Effect modification by risk of bronchopulmonary dysplasia

LW Doyle, HL Halliday, RA Ehrenkranz, PG Davis, JC Sinclair

Journal of Pediatrics | Published : 2014

DOI: 10.1016/j.jpeds.2014.07.049

Abstract

Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.

University of Melbourne Researchers

Lex Doyle Author

Peter Davis Author

Related Projects (2)

IMPROVING THE HEALTH OF NEWBORN INFANTS

Birth is a complex process and sometimes babies require help to make the transition to independent life. Professor Peter Davis is conducting..

IMPROVED RESPIRATORY SUPPORT AND OUTCOMES FOR VERY PRETERM BABIES

Premature babies are born with lungs that are not developed enough to sustain their breathing needs after birth. As a result, they need inte..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

Supported by the National Health and Medical Research Council (NHMRC) of Australia (108700, 606789, and Centre of Research Excellence 1060733) and the Victorian Government's Operational Infrastructure Support Program. P.D. is supported in part by a Practitioner Fellowship (grant 1059111) from the National Health and Medical Research Council. The authors declare no conflicts of interest.